Showing posts with label memory loss. Show all posts
Showing posts with label memory loss. Show all posts

Monday, 29 August 2016

Forgetfulness, memory loss - is the culprit Crestor?

In recent weeks, maybe over a month now, I have noticed a worrying sign, a growing incidence of forgetfulness, issues with my memory.


Now after my triple bypass nine years ago in 2007 I, like many others after such operations, had issues with my memory, something which I soon after found out was not uncommon for people who have had open heart surgery and a condition that was referred to as Postperfusion syndrome or "Pumphead". With me, my short term memory after surgery was absolutely "shot" but remarkably my long term memory seemed to improve.

After a year or two (or was it longer?) the memory issues appeared to go away and I was more or less back to normal.

Fast forward to 2016. Over the past 3-4 weeks (or maybe a bit longer) I have noticed that again I am having issues with my memory, particularly short term. At first I simply didn't pay much attention to this but over the past couple of weeks I feel this has been getting worse and it is starting to concern me.

For example, in conversations with people, if I am talking about something and get interrupted, I can find it very hard to find my line of thought, of what I was talking about and it can take me minutes of serious concentration to remember what I was talking about. This has happened more and more over the past couple of weeks.

More worrying, however, has been a couple of issues regarding my medication and this is something I will need to address if it does not improve or in fact if it gets worse.

A week ago today I started using Ntro-Dur 5 patches to help me with my angina. All good, I followed the instructions and Monday through Thursday I placed the patch on a different part of my upper body as directed.


Then came Friday. On Friday evening I realized I had forgotten to put the patch on that morning. Okay, these things happen and I made a mental note not to do this again.

Then came Sunday, two days later. Normally I put the patch on in the morning after my shower and take it off in the evening - on for 12 hours, no patch for 12 hours as per instructions.


So this morning (Monday morning) I am lying in bed at 5.00am wide awake, feeling good and then it dawns on me that I did not take the patch off last night - it had been on since 10.00am the previous morning for some 17 hours. Now I am not sure what the consequences will be for me today but I do know I will not be putting a patch on today.

BUT the worrying thing is that now, within seven days, I have had two incidences regarding medication that I need to take to help me with my issues, in this case my heart and angina.

And then I remember - oh the irony - that one of the side effects of Crestor is memory issues, forgetfulness. After finding a new 99% blockage in my RCA in May I was changed from Lipitor for my cholesterol to Crestor.

Will monitor this situation and will speak to my GP if this situation does not improve or in fact if it gets worse.

More information on side effects of Crestor can be found here: https://medlineplus.gov/druginfo/meds/a603033.html

Thursday, 7 January 2016

Memory Problems and Heart Disease: Postperfusion Syndrome and Vascular Dementia

Continuing on with a topic I ended 2015 on, Postperfusion “Pumphead” syndrome, memory loss and cognitive issues after open heart surgery.

I recently came across a blog on the internet called “Rehabilitate the Heart” which I felt is very relevant to those of us who have had open heart surgery and more importantly, an article that has relevance to those close to us including spouses, partners and children. 

And given this question of memory loss comes up so often in social media "heart" groups such as Facebook and in cardiac rehab programmes I feel another post on this topic is more than appropriate.

This blog not only continues on with the discussion regarding postperfusion syndrome but also introduces the question of Vascular Dementia.

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"Working in Cardiac Rehabilitation it wasn’t uncommon for a spouse or significant other to come in with the patient on the first day or early on in their rehabilitation and voice concern about the patients memory. It is common during the first three months after open heart surgery to be forgetful, to not remember little things, to be frustrated easily. However, within three months these issues should improve. There are a number of people however who have a steady decline in what we call cognitive health or  show cognitive impairment. They begin to display progress symptoms of dementia. This is very real and it is very scary, for both the patient and the caregiver.

Two common reasons for the mental decline are Pump Head and Vascular Dementia
Postperfusion syndrome, also known as “pumphead” is an impairment of cognitive symptoms attributed to Open Heart Surgery. Symptoms of postperfusion syndrome are subtle and include defects associated with attention, concentration, short term memory, fine motor function, and speed of mental and motor responses. Studies have shown a high incidence of these issues soon after surgery, but the deficits are often short lived with no permanent damage and last only a few months. It is when the symptoms persist beyond the first few months are concerning.

The symptoms of pumphead include:
·        difficulty in concentrating
·        increased depression
·        short term memory deficit
·        slower speed of mental and motor responses

“Pumphead”  refers to the state in which patients seem to linger after being hooked up to a heart-lung machine for open-heart or valve surgery.  The clinical term for pumphead is cognitive impairment after coronary artery bypass grafting (CABG). Other symptoms include poor recall, social difficulties and personality changes. Pumphead is when after an initial recovery of mental capabilities in the first few months, the condition often worsens later and persists for years.

Cognitive training may improve memory and reasoning in patients after CABG  

Thus the new area of rehabilitation, cognitive rehabilitation, such as after an acute injury to the brain like a closed head injury or a stroke.
"A new study results confirm that older adults who undergo CABG experience postoperative cognitive decline but show that cognitive training improves memory and attention, suggesting that this training can be a useful rehabilitation tool.
Cognitive training is a “burgeoning business,” much of which involves computer-based puzzles and brain games. While there’s a lot of suggestive evidence of an association between mental stimulation and lower risk for dementia, “we need to do more science around it to find out what works and what doesn’t work,”
http://www.theheart.org/article/1454099.do 





Is it Pump Head or Vascular Dementia?
Inadequate blood flow can damage and eventually kill cells anywhere in the body. The brain has one of the body’s richest networks of blood vessels and is especially vulnerable.
In vascular dementia, changes in thinking skills sometimes occur suddenly following strokes that block major brain blood vessels. Thinking problems also may begin as mild changes that worsen gradually as a result of multiple minor strokes or other conditions that affect smaller blood vessels, leading to cumulative damage. A growing number of experts prefer the term “vascular cognitive impairment (VCI)” to “vascular dementia” because they feel it better expresses the concept that vascular thinking changes can range from mild to severe.

Vascular brain changes often coexist with changes linked to other types of dementia, including Alzheimer’s disease."

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